Research Fellow – AR2317DD
CRISPR-Cas is a prokaryotic adaptive immune
system with exciting applications in genome engineering. The CRISPR-Cas system
is far more complex than just Cas9, and many fundamental questions about its
mechanism remain unresolved. We are focused on type III CRISPR systems that
operate by detecting foreign RNA and generating a cyclic nucleotide second
messenger. We wish to recruit a research fellow to study the molecular biology
of the CRISPR system and in particular focus on the mechanism by which cyclic
nucleotides are sensed as a signal of viral infection by effector proteins. The
successful applicant will have a PhD degree in the Life Sciences and experience
in the areas of biochemistry, molecular biology and molecular microbiology. Experience
in the areas of protein:nucleic acid interactions or phage:host interactions
would be advantageous.
The post, which is available from 1st
April 2020 for up to 2 years, is funded by the BBSRC. This project is based in
the laboratory of Professor Malcolm White in the Biomedical Sciences Research
Complex (BSRC) at the University of St Andrews. You will join a well-funded,
enthusiastic and friendly group working on aspects of the CRISPR system.
Informal enquiries are strongly encouraged and
can be made to Professor Malcolm White (e-mail: mfw2@st-andrews.ac.uk).
The University is
committed to equality for all, demonstrated through our working on diversity
awards (ECU Athena SWAN/Race Charters; Carer Positive; LGBT Charter; and
Stonewall). More details can be found at
http://www.st-andrews.ac.uk/hr/edi/diversityawards/.
Closing Date: 2 March 2020
Interview
Date: To be confirmed
Please quote ref: AR2317DD
Further particulars: AR2317DD FPs.doc
School of Biology
Salary: £33,797 – £40,322 per annum
Start Date: 1 April 2020
Fixed Term: Up to 24 months
Research Fellow – AR2317DD